

Scientific evidence
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Performance of the 23-gene expression profile (23-GEP) test by histopathological evaluation in an independent, multi-center performance cohort of cutaneous melanocytic neoplasms
11/13/2023
Accuracy data in an independent, multi-center cohort of 2512 melanocytic lesions
MyPath Melanoma
Cutaneous Melanoma
Validation
Diagnostic
Dermatology
Poster
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An Automated Tissue Systems Pathology Test Can Standardize the Management and Improve Health Outcomes for Patients With Barrett's Esophagus
11/1/2023
Management guided by the TSP-9 test can standardize care plans by increasing the early detection of progressors who can receive therapeutic interventions, while also increasing the percentage of nonprogressors who can avoid unnecessary therapy and be managed by surveillance alone.
TissueCypher
Barrett's Esophagus
Prognostic
Gastroenterology
Publication
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A Dermatologist’s Guide to Implementation of Gene Expression Profiling in the Management of Melanoma
11/1/2020
Expert panel of 5 leading dermatologists with 31-GEP experience convened to review literature and create a shared decision-making model/algorithm.
DecisionDx-Melanoma
Cutaneous Melanoma
Guidelines
Prognostic
Dermatology
Publication
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Management Decisions Made by Physician Assistants and Nurse Practitioners in Cutaneous Malignant Melanoma Patients: Impact of a 31-Gene Expression Profile Test
11/1/2018
Survey to determine the impact of 31-GEP test results on management decisions made by dermatology PA/NPs for cutaneous melanoma patients.
DecisionDx-Melanoma
Cutaneous Melanoma
Other
Prognostic
Dermatology
Publication
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Integrating the melanoma 31-gene expression profile test with surgical oncology practice within national guideline and staging recommendations
10/6/2020
Define changes in clinical management resulting from the use of the prognostic 31-gene expression profile (31-GEP) test for cutaneous melanoma in a surgical oncology practice.
DecisionDx-Melanoma
Cutaneous Melanoma
Clinical Utility
Prognostic
Dermatology
Publication
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Imported item 91
10/25/2019
TissueCypher risk stratified BE patients with a community-based diagnosis of LGD with an accuracy comparable to three renowned expert pathologists.
TissueCypher
Validation
Prognostic
Gastroenterology
Poster
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Evaluation of Additional Spatial and Temporal Information Increases the Overall Accuracy of an Objective Risk Prediction Assay in Patients with Non-Dysplastic Barrett’s Esophagus (POSTER PRESENTATION AT ACG 2019 ANNUAL MEETING, SAN ANTONIO, TX P0269)
10/25/2019
TissueCypher may be a effective solution to aid decision-making on surveillance intervals and therapeutic interventions in the management of NDBE patients.
TissueCypher
Barrett's Esophagus
Validation
Prognostic
Gastroenterology
Poster
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A Cost-Effectiveness Analysis of an Adenocarcinoma Risk Prediction Multi-Biomarker Assay for Patients with Barrett’s Esophagus
10/25/2019
The TissueCypher assay would be cost-effective after 5 years and improves patient outcomes by improving effectiveness of surveillance and treatment protocols.
TissueCypher
Barrett's Esophagus
Review Article
Prognostic
Gastroenterology
Publication
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The TissueCypher® Barrett’s Esophagus Assay Impacts Clinical Decisions in the Management of Patients with Barrett’s Esophagus
10/21/2021
The TissueCypher test may enable physicians to target EET for high-risk BE patients, while reducing unnecessary procedures in low-risk patients.
TissueCypher
Barrett's Esophagus
Clinical Utility
Prognostic
Gastroenterology
Publication
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An independent validation of a gene expression signature to differentiate malignant melanoma from benign melanocytic nevi
10/21/2016
Establishes the performance of the gene expression signature in prospectively submitted cases with triple concordant diagnosis
MyPath Melanoma
DiffDx-Melanoma
Cutaneous Melanoma
Validation
Diagnostic
Dermatology
Publication
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The i31-GEP identifies patients with T1 cutaneous melanoma who can safely avoid sentinel lymph node biopsy: Results from a prospective, multicenter study
10/2024
DecisionDx-Melanoma
Cutaneous Melanoma
Validation
Prognostic
Dermatology
Presentation
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Use of the 40-gene expression profile (40-GEP) test to identify immune suppressed patients with Brigham and Women’s Hospital (BWH) T1-T2a cutaneous squamous cell carcinoma (cSCC) at higher risk of metastasis: Implications for adjuvant radiation
10/2024
DecisionDx-SCC further stratified immune suppressed patients with T2a tumors into those with more favorable (Class 1 test result; 3-yr MFS of 83%) and less favorable survival (Class 2A/2B test result; 3-yr MFS of 57%). Given the study data, treatment intensification such as ART should be strongly considered in immune suppressed patients with BWH T2a SCC tumors guided by DecisionDx-SCC test results.
DecisionDx-SCC
Cutaneous Squamous Cell Carcinoma
Validation
Prognostic
Dermatology
Presentation
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