Scientific evidence

Impact of gene expression profile testing on the management of squamous cell carcinoma by dermatologists

Oct 2019

To determine the impact of cSCC-GEP test results on management decisions made by dermatologists for cSCC patients.

Author: Teplitz R, et al.

Publication: JDD

Guidelines of care for the management of cutaneous squamous cell carcinoma

Feb 2018

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human cancer and has an increasing annual incidence. Although most cSCC is cured with office-based therapy, advanced cSCC poses a significant risk for morbidity, impact on quality of life, and death. This document provides evidence-based recommendations for the management of patients with cSCC. 

Author: Alam M, et al.

Publication: J Am Acad Dermatol

The treatment of actinic keratoses — the rule rather than the exception

Nov 2017

This work highlights a critical aspect of the physician-patient relationship—communication. As expected, the findings suggest that the verbiage used to describe actinic keratoses (AKs) can affect the patient’s decision to pursue treatment. Interestingly, regardless of how the question was framed, most patients preferred to treat these lesions.

Author: Mansouri B, et al.

Publication: JAMA Dermatol

Evaluation of American Joint Committee on Cancer, International Union Against Cancer, and Brigham and Women's Hospital tumor staging for cutaneous squamous cell carcinoma

Dec 2013

To compare American Joint Committee on Cancer (AJCC), International Union Against Cancer (UICC), and Brigham and Women's Hospital (BWH) tumor (T) staging systems for cutaneous squamous cell carcinoma and validate BWH staging against prior data.

Author: Karia P, et al.

Publication: Journal of Clinical Oncology

AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for MOHS micrographic surgery: A report of the American Academy of Dermatology, American College of MOHS Surgery, American Society for Dermatologic Surgery Association, and the American Society for MOHS Surgery

Oct 2012

The appropriate use criteria process synthesizes evidence-based medicine, clinical practice experience, and expert judgment. The American Academy of Dermatology in collaboration with the American College of Mohs Surgery, the American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery has developed appropriate use criteria for 270 scenarios for which Mohs micrographic surgery (MMS) is frequently considered based on tumor and patient characteristics.

Author: Connolly S, et al.

Publication: J Am Acad Dermatol