Scientific evidence

Clinical validation of a gene expression signature that differentiates benign nevi from malignant melanoma

Mar 2015

Initial development and validation of the 23-GEP establishing a high level of sensitivity and specificity in a broad range of histopathological subtypes.

Author: Clarke L, et al.

Publication: Journal of Cutaneous Pathology

Gene expression profiling for molecular staging of cutaneous melanoma in patients undergoing sentinel lymph node biopsy

Mar 2015

Assessment of the prognostic accuracy of GEP and sentinel lymph node biopsy (SLNB) tests, independently and in combination, in a multicenter cohort of 217 patients.

Author: Gerami P, et al.

Publication: Journal of the American Academy of Dermatology

Analytical validation of a melanoma diagnostic gene signature using formalin-fixed paraffin-embedded melanocytic lesions

Mar 2015

Analytical validation study to establish precision, dynamic range, RNA yield, reproducibility, and melanin inhibition.

Author: Warf M, et al.

Publication: Biomarkers in Medicine

Development of a prognostic genetic signature to predict the metastatic risk associated with cutaneous melanoma

Jan 2015

Multicenter study shows clear and significant separation of risk between Class 1 and Class 2 result for DFS, DMFS, MSS, OS using Kaplan-Maier analysis.

Author: Gerami P, et al.

Publication: Clinical Cancer Research