Cases with John Lipham, MD

Developing an algorithm for Barrett’s esophagus

John Lipham, MD, is a professor of clinical surgery and chief of upper GI and general surgery at Keck School of Medicine of USC. Since adopting TissueCypher, he and his team have developed an algorithm for managing patients with non-dysplastic Barrett’s esophagus.

“It’s helping to decrease overutilization of endoscopy and surveillance [for low-risk patients],” says Dr. Lipham.

“On the other hand, if they come back as intermediate or high risk… those are the patients that are jumping at the chance to get rid of their Barrett’s at that point because they now know that their risk is higher than the standard non-dysplastic patient.”

See Dr. Lipham's TissueCypher case studies

Helping an older patient be proactive in preventing EAC

An 81-year old male patient found himself on the fence about whether to continue ongoing surveillance of his BE. Up to this point he had no family history of EAC or even a diagnosis of dysplasia that would give him an objective reason to seek more aggressive management of his BE.

Read the case details below.

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Confirming low risk of progression in a young female patient

Listen to how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett's esophagus.

"We're going to be seeing more of these patients that don't quite fit that demographic profile of your typical patient with Barrett's — expect to see more people like this."

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If they come back as intermediate or high risk... those are the patients that are jumping at the chance to get rid of their Barrett's at that point because they now know that their risk is higher than the standard non-dysplastic patient.

John C. Lipham, MD