

Scientific evidence
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Real-world evidence confirms risk stratification of the 31-GEP and i31-GEP in prospectively tested patients with stage I-III cutaneous melanoma
January 1, 2024
DecisionDx-Melanoma
Cutaneous Melanoma
Author: Pariser D, et al.
Publication: Presented at the 2024 Winter Clinical Dermatology Conference - Hawaii®, Honolulu, Hawaii, January 12-17, 2024
Clinical Utility
Prognostic
Dermatology
Poster
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A randomized controlled study on clinical adherence to evidence-based guidelines in the management of simulated patients with Barrett’s esophagus and the clinical utility of a tissue systems pathology test: results from Q-TAB
January 1, 2024
TissueCypher optimized adherence to clinical guidelines for surveillance and treatment of both BE patients at high and low risk for disease progression. Use of the test can enable physicians to make risk-aligned management decisions, leading to improved patient health outcomes.
TissueCypher
Barrett's Esophagus
Author: Peabody J, et al.
Publication: Clinical and Translational Gastroenterology
Validation
Prognostic
Gastroenterology
Publication
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Gene expression differences identified in skin samples of mycosis fungoides, atopic dermatitis, and psoriasis.
January 1, 2024
Gene Expression Differences Identified in Skin Samples of Mycosis Fungoides, Atopic Dermatitis, and Psoriasis.
Other
Cutaneous Squamous Cell Carcinoma
Author: Farberg A, et al.
Publication: Presented at the 2024 Winter Clinical Dermatology Conference - Hawaii®, Honolulu, Hawaii, January 12-17, 2024
Clinical Utility
Prognostic
Dermatology
Presentation
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Diagnostic discordance among histopathological reviewers for difficult-to- diagnose melanocytic lesions
January 1, 2024
MyPath Melanoma
Cutaneous Melanoma
Author: Hosler G, et al.
Publication: Presented at the 2024 Winter Clinical Dermatology Conference - Hawaii®, Honolulu, Hawaii, January 12-17, 2024
Clinical Utility
Diagnostic
Dermatology
Presentation
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Use of the 40-gene expression profile (40-GEP) test in medicare-eligible patients diagnosed with cutaneous squamous cell carcinoma (cSCC) to guide adjuvant radiation therapy (ART) decisions leads to a significant reduction in healthcare costs
January 1, 2024
Utilizing the 40-GEP test results to guide ART decision-making would result in material savings to Medicare.
DecisionDx-SCC
Cutaneous Squamous Cell Carcinoma
Author: Somani, A, et al.
Publication: Journal of Clinical and Aesthetic Dermatology
Clinical Utility
Prognostic
Dermatology
Publication
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The 40-gene expression profile (40-GEP) test identifies cutaneous squamous cell carcinoma (cSCC) patients at high risk of metastasis within lower-staged tumors to better guide treatment decisions
January 1, 2024
DecisionDx-SCC
Cutaneous Squamous Cell Carcinoma
Author: Somani, A, et al.
Publication: Presented at the 2024 Winter Clinical Dermatology Conference - Hawaii®, Honolulu, Hawaii, January 12-17, 2024
Clinical Utility
Prognostic
Dermatology
Poster
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The 31-gene expression profile test outperforms AJCC in stratifying risk of recurrence in patients with stage I cutaneous melanoma
January 1, 2024
In a head-to-head comparison of DecisionDx-Melanoma to AJCCv8 staging for stage I cutaneous melanoma (CM) patients (n=6,883) two cohorts were analyzed using recurrence-free survival and melanoma-specific survival. Results from the study showed that DecisionDx-Melanoma significantly improved patient risk stratification, independent of AJCC staging in patients. In addition, DecisionDx-Melanoma provided greater separation between high-risk (Class 2B) and low-risk (Class 1A) groups than seen between AJCC stage IA and IB.
DecisionDx-Melanoma
Cutaneous Melanoma
Clinical Utility
Prognostic
Dermatology
Publication
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Incorporating a prognostic gene expression profile test into the mangement of cutaneous squamous cell carcinoma: An expert consensus panel report
December 1, 2023
DecisionDx-SCC
Cutaneous Squamous Cell Carcinoma
Clinical Utility
Prognostic
Dermatology
Publication
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Diagnostic utility of the 23-gene expression profile test for an atypical intradermal melanocytic proliferation
December 1, 2023
A case report describing how MyPath GEP testing leads to diagnostic clarity in a histopathologically ambiguous melanocytic lesion on the face of a 34-year-old man.
MyPath Melanoma
Cutaneous Melanoma
Clinical Utility
Diagnostic
Dermatology
Publication
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A physician’s guide to the use of gene expression profile ancillary diagnostic testing for cutaneous melanocytic neoplasms
December 1, 2023
A real-world assessment of common use scenarios of MyPath GEP testing by dermatopathologists and dermatologists to achieve definitive diagnoses and personalized patient management plans.
DecisionDx-Melanoma
MyPath Melanoma
Cutaneous Melanoma
Author: Marks E, et al.
Publication: Journal of Clinical and Aesthetic Dermatology
Clinical Utility
Diagnostic
Dermatology
Publication
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Performance of the 23-gene expression profile (23-GEP) test by histopathological evaluation in an independent, multi-center performance cohort of cutaneous melanocytic neoplasms
November 13, 2023
Accuracy data in an independent, multi-center cohort of 2512 melanocytic lesions
MyPath Melanoma
Cutaneous Melanoma
Validation
Diagnostic
Dermatology
Poster
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An Automated Tissue Systems Pathology Test Can Standardize the Management and Improve Health Outcomes for Patients With Barrett's Esophagus
November 1, 2023
Management guided by the TSP-9 test can standardize care plans by increasing the early detection of progressors who can receive therapeutic interventions, while also increasing the percentage of nonprogressors who can avoid unnecessary therapy and be managed by surveillance alone.
TissueCypher
Barrett's Esophagus
Prognostic
Gastroenterology
Publication
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