Listen to how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett's esophagus.
"We're going to be seeing more of these patients that don't quite fit that demographic profile of your typical patient with Barrett's — expect to see more people like this."
Listen to how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett's esophagus.
"We're going to be seeing more of these patients that don't quite fit that demographic profile of your typical patient with Barrett's — expect to see more people like this."
Listen to how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett's esophagus.
"We're going to be seeing more of these patients that don't quite fit that demographic profile of your typical patient with Barrett's — expect to see more people like this."
Listen to how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett's esophagus.
"We're going to be seeing more of these patients that don't quite fit that demographic profile of your typical patient with Barrett's — expect to see more people like this."
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A 19-year-old female patient presented to Dr. Yepuri with intermittent solid dysphasia and issues with nocturnal reflux. With no concern for family history of esophageal cancer, smoking, or PPI use, her clinical risk profile appeared to be low risk.
Given her symptoms, Dr. Yepuri performed an upper endoscopy and found a C1M0 Prague classification of Barrett's esophagus (BE) with LA Grade A esophagitis but no hiatal hernia. Pathology came back as non-dysplastic BE. The BE diagnosis was surprising at such a young age, so appropriate risk stratification would be key to management.
TissueCypher results revealed an individual low-risk classification, with a risk score of 4.1 and a 3% probability of progression. This helped to provide assurance that the appropriate care plan was guideline-based surveillance every 3 years, repeating TissueCypher testing every other interval.
TissueCypher-guided management
Jay Yepuri, MD, FACG
