Case Studies

See how objective data from TissueCypher can help improve care for Barrett's esophagus patients

Read through this collection of case studies from various clinicians who have ordered TissueCypher for their patients. Each case includes an overview of clinical risk factors, endoscopic findings, and TissueCypher-guided care plans.

Case studies by provider

Cases with Helena in’t Veld, MSN, FNP-C

View three cases where an advanced practice provider found value in TissueCypher testing

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Cases with John Lipman, MD

Dr. Lipham shares two cases where TissueCypher guided his patient management

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Cases with Charles Loewe, MD

View three case studies illustrating how objective data from TissueCypher helped to advance patient care.

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Cases with Jay Yepuri, MD, FACG

View three case studies demonstrating the clinical benefit of TissueCypher testing.

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Cases with Daniel Tseng, MS, FACS

View two case studies illustrating how objective data from TissueCypher helped to advance patient care.

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All case studies

A patient with multiple EGDs and conflicting endoscopic findings

This case of a 75-year-old female required Dr. Yepuri to weigh multiple conflicting data points to recommend the best care for an anxious patient.

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A patient with a family history of esophageal adenocarcinoma

A patient with non-dysplastic BE and a family history of EAC that wanted reassurance prior to moving forward with EET.

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Anxious female patient with concerning family history

Helena uses TissueCypher to reveal low risk of progression to an anxious patient that routinely asks to shorten her Barrett’s esophagus surveillance interval.

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Confirming low risk of progression in a young female patient

See how Dr. Yepuri handled the case of a young female patient who received an unexpected diagnosis of Barrett’s esophagus.

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Downstaging a female patient with elevated clinical risk

A 60-year-old female with a complicated medical history is reassured by a low-risk TissueCypher score to extend BE surveillance intervals.

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Downstaging a patient referral for radio-frequency ablation

This case of a 52-year-old male gives an example of how the decision on whether or not to pursue EET is not always clear.

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Helping a 56-year-old patient take his esophageal cancer risk seriously

Helena helped a patient who was skeptical of his condition to act on his high risk of malignant progression.

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Helping an older patient be proactive in preventing EAC

An 81-year-old male patient found himself on the fence about whether to continue ongoing surveillance of his BE.

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High anxiety and difficulty swallowing

Dr. Loewe discusses a patient with a 25-year history of GERD, non-dysplastic Barrett’s esophagus, and difficulty swallowing.

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Younger patient, long-segment with TissueCypher low risk

A 38-year-old male with long-segment Barrett’s esophagus and a low-risk TissueCypher emphasized the need to consider all the factors of the case.

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Older patient, short-segment with TissueCypher high risk

Dr. Lipham shares the case of a 77-year-old patient who appeared to have low clinical risk but received a high-risk TissueCypher score.

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TissueCypher reveals a missing critical detail

A 69-year-old male patient was anxious about his BE, and a TissueCypher high-risk score led to a revealing discussion.

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