Search
Clinician Ordering Portal
Our test
DecisionDx-UM accurately predicts the risk of your eye cancer spreading
One of the primary challenges for healthcare providers in managing uveal melanoma is predicting the potential for the disease to spread.
Fortunately, patients today have access to the DecisionDx-UM gene expression profile (GEP) test, which predicts a patient’s risk based upon their tumor’s own unique biology. The test was developed by ocular oncologist Dr. J. William Harbour, currently at UT Southwestern Medical Center, and exclusively licensed to Castle Biosciences Inc.
DecisionDx-UM uses tumor biology to more accurately predict the risk of your cancer recurring or spreading
DecisionDx-UM is the most widely used prognostic test in uveal melanoma in the U.S. It is used to predict risk of a patient’s tumor spreading in five years. Several studies published in peer-reviewed journals, including Melanoma Management and Ocular Oncology and Pathology found that the DecisionDx-UM test has a significant impact on the management of uveal melanoma. Ophthalmologists report that they are more likely to increase frequency of disease monitoring or recommend clinical trials for those patients whose test results showed they were at high risk of metastasis.
Class Score
The DecisionDx-UM test is extremely valuable in guiding a patient’s care following treatment of the original eye tumor. It measures the activity or “expression” of certain genes within the tumor to determine its risk profile, or Class:
-
Class 1A
Low risk
With a 2% risk of spreading over the next five years
-
class 1b
intermediate risk
With a 21% risk of spreading over the next five years
-
class 2a
high risk
With a 72% risk of spreading over the next five years
Genomic testing adoption by healthcare professionals
Since its availability in 2009, over 16,000 patients have been clinically tested with DecisionDx-UM, making it the most widely used uveal melanoma prognostic test in the US. To date, more than 300 healthcare providers have used DecisionDx-UM to help guide the management of their patient's cancer.
See if DecisionDx-UM is right for you
It's your decision
Your Healthcare Professional is a trusted source of information. But the decision to get tested is yours to make. Download the Discussion Guide for some helpful tips on how to start the conversation.
