Scientific evidence

A tissue systems pathology assay for high-risk Barrett’s esophagus

May 2016

Exploration of a tissue systems pathology approach to predict progression in patients with non-dysplastic Barrett's esophagus.

Author: Critchley-Thorne RJ, et al.

Publication: Cancer Epidemiology, Biomarkers & Prevention

A tissue systems pathology test detects a field effect associated with high-grade dysplasia and esophageal cancer in Barrett’s esophagus patients

May 2016

TissueCypher better predicts the presence of HGD and EAC in BE than pathologic variables and can improve histology to identify patients requiring therapy.

Author: Critchley-Thorne RJ, et al.

Publication: Poster presentation (Sa1257) at DDW 2016, San Diego

A cost-effectiveness analysis of a test that predicts risk of malignant progression in Barrett’s esophagus

May 2016

TissueCypher is cost-saving after five years and improves patient outcomes due to improving the effectiveness of surveillance and treatment.

Author: Hao J, et al.

Publication: Podium presentation (CN4) at ISPOR 2016, Washington DC

A tissue systems pathology test detects a field effect associated with high grade dysplasia and esophageal cancer in Barrett’s esophagus patients

May 2016

TissueCypher better predicts presence of HGD and EAC in BE than pathologic variables, and can improve on histology to identify patients requiring therapy.

Author: Critchley-Thorne RJ, et al.

Publication: Poster presentation (Sa1257) at DDW 2016, San Diego

A novel tissue systems pathology test predicts progression in Barrett’s esophagus patients

Apr 2016

TissueCypher better predicts progression in BE than clinicopathologic variables, and can improve on histology as a method to risk stratify patients with BE.

Author: Critchley-Thorne RJ, et al.

Publication: Podium presentation (301) at DDW 2016, San Diego

A cost-effectiveness analysis of a cancer risk prediction test for patients with Barrett’s esophagus

Apr 2016

The individualized risk prediction test has the potential to improve the efficiency of endoscopic surveillance in BE and to enable early intervention as needed.

Author: Hao J, et al.

Publication: Poster presentation (Sa 1261) at DDW 2016, San Diego

A novel tissue systems pathology test predicts progression in Barrett’s esophagus patients

Apr 2016

TissueCypher better predicts progression in BE than clinicopathologic variables, and can improve on histology as a method to risk stratify patients with BE.

Author: Critchley-Thorne RJ, et al.

Publication: Podium presentation (301) at DDW 2016, San Diego

TissueCypher: a systems biology approach to anatomic pathology

Dec 2015

A quantitative, multiplexed biomarker imaging approach termed TissueCypher™ that applies systems biology to anatomic pathology.

Author: Prichard J, et al.

Publication: Journal of Pathology Informatics